Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992343 | 0.88 | MEN1 (0.52) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL29996949 | 0.87 | MEN1 (0.54) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL2356655 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL1111671 | 0.86 | HTT (0.39) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL29720234 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL28886950 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL411942 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| Sulfuric Acid SCHEMBL2325415 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| SCHEMBL4363083 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPK1MEN1APAF1NPC1 | |
| Sulfuric Acid SCHEMBL1828230 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | claimed |
| US-8642778-B2 | Ionic liquids | MERCK PATENT GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-20110152537-A1 | IONIC LIQUIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2279192-A2 | IONIC LIQUIDS | Merck Patent GmbH (DE) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009152902-A2 | IONIC LIQUIDS | MERCK PATENT GMBH, (DE) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152537-A1 | IONIC LIQUIDS | HCN3, CHRNA3, CHRM3 | SMN1; SMN2 1636/4885MAPK1 1533/4885MEN1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.