SCHEMBL11116928

SCHEMBL11116928

C=C(C=CC#N)C(=O)OCC.C=COC(=O)CCl

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C9 P11712 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinyl Chloride SCHEMBL5430946 0.84 ALDH1A1 (0.47) ALDH1A1TSHRCYP2C9NPSR1
SCHEMBL2260103 0.84 ALDH1A1 (0.53) ALDH1A1TSHRCYP2C9NPSR1
Acrylic Acid SCHEMBL10969441 0.80 ALDH1A1 (0.46) ALDH1A1TSHRCYP2C9NPSR1
Acrylic Acid Ethyl Ester SCHEMBL11116930 0.78 TSHR (0.37) ALDH1A1TSHRNPSR1
Methacrylic Acid SCHEMBL6231308 0.77 ALDH1A1 (0.42) ALDH1A1TSHRCYP2C9NPSR1
Acrylic Acid Methyl Ester SCHEMBL9453506 0.74 ALDH1A1 (0.38) ALDH1A1TSHRCYP2C9
SCHEMBL3742848 0.74 TSHR (0.58) ALDH1A1TSHRNPSR1
Acrylic Acid Ethyl Ester SCHEMBL7182126 0.74 TSHR (0.43) ALDH1A1TSHRNPSR1
SCHEMBL8047550 0.74 MAPT (0.39) ALDH1A1TSHRNPSR1
Acrylonitrile SCHEMBL7869589 0.73 ALDH1A1 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0108223-A1 Sulfur-vulcanizable chlorinated polyethylene-acrylate copolymer graft elastomer AMERICAN CYANAMID COMPANY (US) 1984-05-16 EP disclosed