SCHEMBL11118931

SCHEMBL11118931

CCN(C)C(=O)Nc1cc(C(C)(CC)CC)ns1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMARCA2 P51531 1/20 0.32
SMARCA4 P51532 1/20 0.32
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11117030 0.89 RPS6KA2 (0.36) SMARCA2SMARCA4
SCHEMBL11121353 0.88 ABCC1 (0.37) SMARCA2SMARCA4
SCHEMBL11116703 0.84 MEN1 (0.37) SMARCA2SMARCA4
SCHEMBL11123087 0.82 NPY5R (0.40) SMARCA2SMARCA4
SCHEMBL11119037 0.76 RPS6KA2 (0.36) SMARCA2SMARCA4
SCHEMBL11119728 0.76 ABCC1 (0.38) SMARCA2SMARCA4
SCHEMBL11118761 0.76 ALDH1A1 (0.32)
SCHEMBL11118756 0.75 SMARCA2 (0.33) SMARCA2SMARCA4
SCHEMBL11118060 0.74 SMARCA2 (0.33) SMARCA2SMARCA4
SCHEMBL11119842 0.74 SMARCA2 (0.39) SMARCA2SMARCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129408-A2 (3-alkyl-5-isothiazolyl)ureas ELI LILLY AND COMPANY (US) 1984-12-27 EP disclosed