Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 9/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117327 | 1.00 | PTPRC (0.38) | PTPRCMEN1MAPTMAPK1KMT2A | |
| SCHEMBL11113798 | 0.80 | TRPA1 (0.35) | CDC25ATRPA1 | |
| SCHEMBL677773 | 0.78 | MEN1 (0.42) | PTPRCMEN1MAPTKMT2ACDC25A | |
| SCHEMBL29454416 | 0.78 | MEN1 (0.42) | PTPRCMEN1MAPTKMT2ACDC25A | |
| SCHEMBL130160 | 0.78 | TRPA1 (0.44) | CDC25ATRPA1HDAC3HDAC4HDAC1 | |
| Maleic Acid SCHEMBL11774758 | 0.73 | LMNA (0.56) | MEN1MAPTKMT2A | |
| Fumaric Acid SCHEMBL11774768 | 0.73 | LMNA (0.56) | MEN1MAPTKMT2A | |
| Maleic Acid SCHEMBL11774763 | 0.73 | LMNA (0.56) | MEN1MAPTKMT2A | |
| SCHEMBL4981378 | 0.72 | MEN1 (0.52) | MEN1KMT2A | |
| Oxalic Acid SCHEMBL11728067 | 0.72 | LMNA (0.58) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |