Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688142 | 0.85 | ESR1 (0.62) | KMT2ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL19475609 | 0.83 | KMT2A (0.68) | KMT2APKMMAPTALDH1A1CES1 | |
| SCHEMBL2885963 | 0.83 | ALOX5 (0.63) | KMT2APKMMAPTALDH1A1CES1 | |
| SCHEMBL10689859 | 0.82 | MAPT (0.58) | KMT2APKMNPC1MAPTALDH1A1 | |
| SCHEMBL10377804 | 0.80 | ESR1 (0.57) | KMT2AMAPTALDH1A1CES2MEN1 | |
| SCHEMBL9156958 | 0.80 | NR1H4 (0.53) | KMT2APKMMAPTALDH1A1CES1 | |
| SCHEMBL9316017 | 0.80 | KMT2A (0.49) | KMT2APKMNPC1MAPTALDH1A1 | |
| SCHEMBL1918507 | 0.79 | KMT2A (0.71) | KMT2AMAPTALDH1A1MEN1GAA | |
| SCHEMBL5973956 | 0.79 | ALOX5 (0.73) | KMT2APKMMAPTALDH1A1CES1 | |
| SCHEMBL7748386 | 0.79 | KMT2A (0.67) | KMT2ANPC1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444844-A | LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY | RICOH CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |