Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117550 | 0.83 | KMT2A (0.57) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL9644263 | 0.82 | KMT2A (1.00) | KMT2AMAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2885963 | 0.81 | ALOX5 (0.63) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL5973956 | 0.81 | ALOX5 (0.73) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL10689859 | 0.81 | MAPT (0.58) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL9316017 | 0.78 | KMT2A (0.49) | KMT2AMAPTCES1CES2PKM | |
| SCHEMBL9156958 | 0.78 | NR1H4 (0.53) | KMT2AMAPTCES1CES2PKM | |
| SCHEMBL21999716 | 0.78 | KMT2A (0.77) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL19509566 | 0.78 | KMT2A (0.77) | KMT2AMAPTSMN1; SMN2CES1CES2 | |
| SCHEMBL527544 | 0.78 | KMT2A (0.71) | KMT2AMAPTSMN1; SMN2CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980754-B2 | Anti-fungal compounds | SAINT LOUIS UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-10980754-B2 | Anti-fungal compounds | SAINT LOUIS UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20190099385-A1 | ANTI-FUNGAL COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2019-04-04 | — | — | US | disclosed |
| US-20190099385-A1 | ANTI-FUNGAL COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2019-04-04 | — | — | US | disclosed |
| WO-2017184752-A1 | ANTI-FUNGAL COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2017-10-26 | — | — | WO | disclosed |
| WO-2017184752-A1 | ANTI-FUNGAL COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099385-A1 | ANTI-FUNGAL COMPOUNDS | ERG28, NANS, DPM1 | KMT2A 3839/4885MAPT 3024/4885SMN1; SMN2 3958/4885 |
| US-10980754-B2 | Anti-fungal compounds | ERG28, NANS, DPM1 | KMT2A 3839/4885MAPT 3024/4885SMN1; SMN2 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.