Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169023 | 0.79 | GPR84 (0.42) | KCNH2GPR84TDP1L3MBTL1CYP2C9 | |
| SCHEMBL3248160 | 0.79 | KCNH2 (0.44) | KCNH2GPR84TDP1L3MBTL1MIF | |
| SCHEMBL2359176 | 0.79 | KCNH2 (0.44) | KCNH2TDP1L3MBTL1NOS2HRH3 | |
| SCHEMBL13978025 | 0.77 | KCNH2 (0.43) | KCNH2GPR84TDP1L3MBTL1MIF | |
| SCHEMBL2364044 | 0.77 | MAPT (0.43) | KCNH2TDP1L3MBTL1MIFCYP2C9 | |
| SCHEMBL11629305 | 0.76 | GPR84 (0.39) | KCNH2GPR84L3MBTL1NOS2CYP2C9 | |
| SCHEMBL8980571 | 0.75 | KCNH2 (0.52) | KCNH2GPR84NOS2HRH3 | |
| SCHEMBL2364312 | 0.74 | KCNH2 (0.40) | KCNH2TDP1L3MBTL1MIFCYP19A1 | |
| SCHEMBL10830973 | 0.72 | KCNH2 (0.44) | KCNH2TDP1L3MBTL1MIFCYP19A1 | |
| Ammonia Solution, Strong SCHEMBL17372911 | 0.71 | KCNH2 (0.42) | KCNH2TDP1L3MBTL1MIFCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099438-A1 | 2-Functionalised diaryl as-triazines useful in therapy | PIERRE FABRE S.A. (FR) | 1984-02-01 | — | — | EP | disclosed |