Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920867 | 0.87 | CA1 (0.43) | CA1CA2CA5ACA9EDNRA | |
| SCHEMBL23569071 | 0.87 | EDNRA (0.49) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL23569216 | 0.85 | EDNRA (0.48) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL11471141 | 0.84 | EDNRA (0.52) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL12319426 | 0.84 | EDNRA (0.52) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL388034 | 0.83 | MAPT (0.55) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL31607236 | 0.83 | EDNRA (0.51) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL8973588 | 0.82 | PKM (0.45) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL11469582 | 0.81 | EDNRA (0.56) | EDNRAMAPTTP53KMT2ALMNA | |
| SCHEMBL11117907 | 0.81 | EDNRA (0.53) | EDNRAMAPTTP53KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170043196-A1 | Fire Extinguishing Composition Comprising Heterocyclic Compounds | XI'AN J&R FIRE FIGHTING EQUIPMENT CO., LTD. (CN) | 2017-02-16 | — | — | US | claimed |
| EP-3095485-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING HETEROCYCLIC COMPOUNDS | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| CN-102020667-B | Method for synthesizing 6-chloro-4-hydroxyl-2-methyl-2H-thieno(2.3.e)-1.2thiazide-1.1-dioxide-3-methyl formate | LIU YULIN | 2013-02-27 | — | — | CN | claimed |
| EP-3986879-B1 | FUSED 1,2-THIAZOLES AND 1,2-THIAZINES WHICH ACT AS NLRP3 MODULATORS | AC IMMUNE SA (CH) | 2024-10-02 | — | — | EP | disclosed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| US-20220378801-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-12-01 | — | — | US | disclosed |
| EP-3986879-A1 | FUSED 1,2 THIAZOLES AND 1,2 THIAZINES WHICH ACT AS NL3P3 MODULATORS | AC Immune SA (CH) | 2022-04-27 | — | — | EP | disclosed |
| CN-114008030-A | Fused 1, 2-thiazoles and 1, 2-thiazines as NLRP3 modulators | AC免疫有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2021123237-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020254697-A1 | FUSED 1,2 THIAZOLES AND 1,2 THIAZINES WHICH ACT AS NL3P3 MODULATORS | AC IMMUNE SA (CH) | 2020-12-24 | — | — | WO | disclosed |
| US-4877440-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| US-4743290-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4701535-A | CHEMICAL INTERMEDIATES FOR HERBICIDES, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0207609-A1 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4599103-A | PRE-AND POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0030142-B1 | HERBICIDAL UREAS, PREPARATION, COMPOSITIONS AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4481029-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0030142-A2 | Herbicidal ureas, preparation, compositions and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |
| US-4028373-A | ARTIFICIAL SWEETNERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378801-A1 | NOVEL COMPOUNDS | NLRP3, IL1B, IL18 | CA1 4311/4885CA2 4210/4885CA5A 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.