SCHEMBL11117945

SCHEMBL11117945

Clc1ccc(CNc2ccccc2)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.62
MAOB P27338 1/20 0.56
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
PLA2G1B P04054 1/20 0.50
POLB P06746 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
MAPT P10636 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.48
TRPV1 Q8NER1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11124212 0.98 FFAR1 (0.60) FFAR1MAOBSLC6A2SLC6A4SLC6A3
Propionic Acid SCHEMBL11464614 0.87 FFAR1 (0.66) FFAR1MAOBMEN1KMT2APTGDR2
Acrylic Acid SCHEMBL11462382 0.86 FFAR1 (0.60) FFAR1MAOBPTGDR2TRPV1
SCHEMBL11510459 0.85 FFAR1 (0.62) FFAR1POLBMAPTALDH1A1MEN1
SCHEMBL11511594 0.84 FFAR1 (0.50) FFAR1MAPTALDH1A1MEN1KMT2A
SCHEMBL951833 0.81 FFAR1 (0.55) FFAR1MAOBSLC6A2SLC6A4SLC6A3
SCHEMBL21799187 0.81 FFAR1 (0.59) FFAR1POLBMAPTALDH1A1MEN1
SCHEMBL20473309 0.81 FFAR1 (0.59) FFAR1MAPTALDH1A1MEN1KMT2A
SCHEMBL18768917 0.81 CYP1A2 (0.59) FFAR1MAPTALDH1A1MEN1CYP1A2
SCHEMBL11511690 0.81 MEN1 (0.60) FFAR1PLA2G1BATG4BMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028305-B1 DIARYL COMPOUNDS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1984-02-01 EP claimed
EP-0028305-A1 Diaryl compounds and pharmaceutical formulations containing them THE WELLCOME FOUNDATION LIMITED (GB) 1981-05-13 EP claimed
EP-3363288-B1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR MOSSES CUREARTH INC (KR) 2022-09-07 EP disclosed
CN-108347925-B Compositions for destroying microalgae or moss 株式会社CUREARTH 2021-07-16 CN disclosed
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus CUREARTH, INC. (KR) 2021-06-29 US disclosed
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus CUREARTH, INC. (KR) 2021-06-29 US disclosed
US-20180271091-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS CUREARTH, INC. (KR) 2018-09-27 US disclosed
EP-3363288-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS Curearth, Inc. (KR) 2018-08-22 EP disclosed
CN-108347925-A composition for destroying microalgae or moss 株式会社CUREARTH 2018-07-31 CN disclosed
EP-0028305-B1 DIARYL COMPOUNDS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1984-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180271091-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS TK1, TRHDE, TK2 FFAR1 4411/4885MAOB 3382/4885SLC6A2 4695/4885
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus TK1, TRHDE, TK2 FFAR1 4411/4885MAOB 3382/4885SLC6A2 4695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.