Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350501 | 0.88 | THRA (0.51) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL11173065 | 0.88 | THRA (0.51) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL8389050 | 0.88 | THRA (0.51) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL30149837 | 0.88 | THRA (0.51) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL8379300 | 0.88 | THRA (0.51) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL6849772 | 0.88 | THRA (0.59) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL1100557 | 0.88 | THRA (0.59) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL8393505 | 0.88 | THRA (0.59) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL4004612 | 0.88 | THRA (0.59) | THRATHRBPPARAPTGS2ALOX5 | |
| SCHEMBL11674754 | 0.88 | THRA (0.59) | THRATHRBPPARAPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469644-A | CATALYTIC OXIDATION OF CORRESPONDING PHOISPHITE | BORG-WARNER CHEMICALS, INC. (US) | 1984-09-04 | — | — | US | disclosed |