Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 5/20 | 0.38 |
| ▸ | PYGM | P11217 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543352 | 0.88 | PYGL (0.38) | PYGLPYGMPOLBMTNR1ARIPK1 | |
| SCHEMBL7564692 | 0.81 | IDO1 (0.46) | DDB1CRBN | |
| SCHEMBL4335722 | 0.79 | GLA (0.47) | PYGLPYGMRIPK1HSD17B10DDB1 | |
| SCHEMBL4332417 | 0.75 | DDB1 (0.48) | PYGLPYGMMTNR1ARIPK1HSD17B10 | |
| SCHEMBL25556417 | 0.74 | NPC1 (0.47) | PYGLPYGMMTNR1ADDB1CRBN | |
| SCHEMBL14614572 | 0.74 | NPC1 (0.47) | PYGLPYGMMTNR1ADDB1CRBN | |
| SCHEMBL4334134 | 0.74 | HSD17B10 (0.53) | PYGLPYGMMTNR1AHSD17B10HTT | |
| SCHEMBL8304087 | 0.72 | HSD17B10 (0.55) | HSD17B10HTTTSHRKDM4EALDH1A1 | |
| SCHEMBL3457244 | 0.72 | NPC1 (0.45) | PYGLPYGMMTNR1ARIPK1DDB1 | |
| SCHEMBL7691772 | 0.71 | NPC1 (0.47) | PYGLPYGMRIPK1HTTDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119955-A2 | 3-(5-Aminopentyl)-amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |