Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571213 | 0.83 | IDO1 (0.46) | IDO1EPHX2CCKARCCKBR | |
| SCHEMBL7565981 | 0.82 | IDO1 (0.52) | IDO1EPHX2CCKARCCKBR | |
| SCHEMBL7543352 | 0.81 | PYGL (0.38) | IDO1DDB1CRBN | |
| SCHEMBL11118089 | 0.81 | PYGL (0.38) | DDB1CRBN | |
| SCHEMBL11133817 | 0.81 | IDO1 (0.51) | IDO1EPHX2CCKARCCKBR | |
| SCHEMBL29481025 | 0.76 | PYGL (0.50) | IDO1SCN9AEPHX2 | |
| SCHEMBL7564705 | 0.74 | IDO1 (0.46) | IDO1CALCRLSCN9AEPHX2CCKAR | |
| SCHEMBL1269023 | 0.74 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL5640963 | 0.74 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL1269022 | 0.74 | EPHX2 (0.56) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |