Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060796 | 0.82 | MAPT (0.79) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11119675 | 0.80 | MAPT (0.47) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11486443 | 0.77 | TDP1 (0.47) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11058008 | 0.76 | ALDH1A1 (0.47) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11063611 | 0.75 | TDP1 (0.42) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11059892 | 0.75 | ALDH1A1 (0.46) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11057788 | 0.74 | MAPT (0.65) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11054655 | 0.74 | MAPT (0.65) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11058159 | 0.70 | MAPT (1.00) | MAPTNPSR1POLBALDH1A1TDP1 | |
| SCHEMBL11056912 | 0.70 | MAPT (1.00) | MAPTNPSR1POLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010420-B1 | PYRIDYL-SUBSTITUTED THIAZOLIDINE AND 1,3-THIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AGRICULTURAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND METHODS FOR REGULATING PLANT GROWTH AND PROTECTING PLANTS FROM FUNGI | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |
| EP-0010420-A1 | Pyridyl-substituted thiazolidine and 1,3-thiazine derivatives, processes for their preparation, agricultural compositions containing said derivatives and methods for regulating plant growth and protecting plants from fungi | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | claimed |