Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 8/20 | 0.53 |
| ▸ | CA9 | Q16790 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567249 | 0.81 | DRD4 (0.58) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL3197214 | 0.79 | DRD4 (0.69) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL9080916 | 0.79 | DRD4 (0.53) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL9081412 | 0.78 | ALDH1A1 (0.55) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL19286434 | 0.77 | GAA (0.54) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL34466955 | 0.77 | DRD4 (0.71) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL27524743 | 0.77 | GLA (0.55) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL9474175 | 0.77 | DRD4 (0.67) | DRD4CA12CA9KDM4ECA1 | |
| Methylamine SCHEMBL27532121 | 0.76 | GLA (0.51) | DRD4CA12CA9KDM4ECA1 | |
| SCHEMBL22899134 | 0.75 | DRD4 (0.69) | DRD4CA12CA9KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014344-B1 | COUMARIN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS WHITENERS AND LASER DYES | BAYER AG (DE) | 1982-04-21 | — | — | EP | claimed |
| EP-0056577-B1 | TRIAZOLYL-COUMARIN DERIVATIVES, THEIR PREPARATION AND USE AS OPTICAL BRIGHTENING AGENTS SCINTILLATORS AND DYESTUFFS FOR LASERS | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4426530-A | Triazolylcoumarin compounds, and their preparation and use as optical brighteners, scintillators and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0056577-A1 | Triazolyl-coumarin derivatives, their preparation and use as optical brightening agents scintillators and dyestuffs for lasers | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
| US-4326066-A | Triazolyl coumarin compounds, processes for their preparation and their use as whiteners and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4229579-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4144243-A | OPTICAL BRIGHTENERS FOR TEXTILES AND LACQUEARS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4005098-A | BRIGHTENING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3968119-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3957817-A | BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |