Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943350 | 0.89 | SIGMAR1 (0.54) | KCNH2TMEM97MEN1KMT2AHTT | |
| SCHEMBL9127520 | 0.85 | KCNH2 (0.59) | KCNH2TMEM97MEN1KMT2AHPGD | |
| SCHEMBL13520306 | 0.83 | SIGMAR1 (0.48) | KCNH2TMEM97HTTCYP2D6CYP2C19 | |
| SCHEMBL13995974 | 0.82 | ALDH1A1 (0.62) | KCNH2TMEM97MEN1KMT2ACYP2D6 | |
| SCHEMBL2257390 | 0.82 | KCNH2 (0.56) | KCNH2TMEM97MEN1KMT2ANPSR1 | |
| SCHEMBL13995946 | 0.82 | ALDH1A1 (0.62) | KCNH2TMEM97MEN1KMT2ACYP2D6 | |
| SCHEMBL2257396 | 0.82 | KCNH2 (0.56) | KCNH2TMEM97MEN1KMT2ANPSR1 | |
| SCHEMBL7855536 | 0.81 | CYP2C19 (0.53) | KCNH2TMEM97MEN1KMT2ACYP2D6 | |
| SCHEMBL6617143 | 0.80 | ITGB1 (0.49) | HTTCYP2D6CYP2C19SMN1; SMN2SIGMAR1 | |
| SCHEMBL21799748 | 0.80 | SIGMAR1 (0.46) | HTTCYP2D6CYP2C19SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118093-A1 | Trichloroacryloyl urea derivatives, process for their preparation and their use as fungicides in agriculture and horticulture | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4036986-A | Fungicidal N-(4-halobenzyl)-N-sec. alkyl-N'-phenylthioureas | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-4010281-A | N-(4-HALOBENZYL)-N-BRANCHED ALKYL-N'-PHENYLUREAS AND FUNGICIDAL USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |