Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951112 | 0.88 | RAB9A (0.77) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL4112548 | 0.86 | EGFR (0.66) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL134635 | 0.83 | RAB9A (0.66) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL4899524 | 0.83 | RAB9A (0.66) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL10202278 | 0.82 | RAB9A (0.64) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL14379217 | 0.82 | RAB9A (0.64) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL2259491 | 0.80 | EGFR (0.62) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL1758718 | 0.80 | EGFR (0.66) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL10804234 | 0.79 | RAF1 (0.62) | RAB9AKMT2ANPC1MEN1MAPK14 | |
| SCHEMBL10930707 | 0.79 | RAB9A (0.61) | RAB9AKMT2ANPC1MEN1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114456-A2 | Acylated isoxazolyl ureas, their preparation, herbicidal formulations containing the same, and a herbicidal method | SHIONOGI & CO., LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |