Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25952455 | 0.84 | LMNA (0.48) | CNR2ALPLKDM4EHTT | |
| SCHEMBL24103989 | 0.82 | CNR2 (0.39) | CNR2ALPLGRIN2BL3MBTL1SLC6A4 | |
| SCHEMBL30916840 | 0.81 | MRGPRX4 (0.44) | MRGPRX4CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL9240089 | 0.81 | NR1I2 (0.47) | CNR2GRIN2B | |
| SCHEMBL2313884 | 0.80 | MRGPRX4 (0.43) | MRGPRX4CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL8396955 | 0.79 | EPHX2 (0.50) | MRGPRX4CNR2ALPLEPAS1SLC6A4 | |
| SCHEMBL22926410 | 0.79 | AR (0.44) | MRGPRX4CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL16373984 | 0.78 | ANO1 (0.46) | CYP1A2CYP2C19CNR2KDM4EEPAS1 | |
| SCHEMBL16953091 | 0.78 | CNR2 (0.36) | CNR2ALPLGRIN2BSLC6A4 | |
| SCHEMBL14237523 | 0.78 | CNR2 (0.36) | CNR2ALPLGRIN2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113625-A1 | Process for the preparation of trifluoromethylated benzenic compounds | RHONE-POULENC CHIMIE (FR) | 1984-07-18 | — | — | EP | disclosed |