Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203437 | 0.87 | HTT (0.40) | MRGPRX4RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11119699 | 0.81 | MRGPRX4 (0.44) | MRGPRX4RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7590939 | 0.80 | CES2 (0.46) | RAB9ACYP1A2CYP2C19PTGDR2KDM4E | |
| SCHEMBL31053746 | 0.80 | CES2 (0.46) | RAB9ACYP1A2CYP2C19PTGDR2KDM4E | |
| SCHEMBL2414121 | 0.76 | PPARG (0.45) | MRGPRX4MAPTGAASLC6A4 | |
| SCHEMBL30446804 | 0.76 | PPARG (0.45) | MRGPRX4MAPTGAASLC6A4 | |
| SCHEMBL17355807 | 0.75 | MRGPRX4 (0.50) | MRGPRX4RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1070284 | 0.75 | PPARG (0.42) | MRGPRX4GAAL3MBTL1 | |
| SCHEMBL30198749 | 0.75 | PPARG (0.42) | MRGPRX4GAAL3MBTL1 | |
| SCHEMBL30506429 | 0.75 | TTR (0.52) | MRGPRX4TP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272285-B | Oxadiazole-containing compound and pharmaceutical composition containing same | 爱思开生物制药株式会社 | 2024-06-07 | — | — | CN | disclosed |