Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301827 | 0.97 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL28392002 | 0.97 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| Hydrochloric Acid SCHEMBL2512939 | 0.97 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL5878784 | 0.97 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| Urea SCHEMBL29192961 | 0.93 | AKR1C4 (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL8467899 | 0.85 | AKR1C4 (0.63) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL29684531 | 0.85 | AKR1C4 (0.63) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL5355330 | 0.85 | SPR (0.55) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL348918 | 0.84 | CYP3A4 (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL3765067 | 0.84 | SMN1; SMN2 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117603604-B | Preparation method of printing gloss oil with amino-terminated hyperbranched self-assembled polyamide as main component | 江苏众立生包装科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117603604-A | Preparation method of printing gloss oil with amino-terminated hyperbranched self-assembled polyamide as main component | 江苏众立生包装科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117586116-A | Preparation method of 2,4, 6-trichlorobenzoic acid | 黑龙江立科新材料有限公司 | 2024-02-23 | — | — | CN | claimed |
| EP-4218413-A2 | NON-AQUEOUS SOLUTION OF PLANT GROWTH REGULATORS AND SEMIPOLAR ORGANIC SOLVENT | Stoller Enterprises, Inc. (US) | 2023-08-02 | — | — | EP | claimed |
| US-20220073742-A1 | FILLED THERMOPLASTIC COMPOSITIONS HAVING IMPROVED FLOW | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-03-10 | — | — | US | claimed |
| CN-112062998-A | Method for manufacturing bamboo fiber wallboard capable of removing formaldehyde and releasing negative ions | 佛山绿森林环保科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-111116617-A | 2,4, 6-terbium trichlorobenzoate complex/calcium carbonate composite fluorescent material and preparation method thereof | 阜阳师范学院 | 2020-05-08 | — | — | CN | claimed |
| EP-1456322-A1 | GLYCERIN TRIESTER PLASTICIZER | FERRO CORPORATION (US) | 2004-09-15 | — | — | EP | claimed |
| EP-0852007-B1 | BORATE STORAGE BUFFER AND SAMPLE DILUENT | BECKMAN COULTER INC (US) | 2004-07-14 | — | — | EP | claimed |
| US-20040006064-A1 | Cephalotaxanes, their method of preparation and their use in treatment of cancers, leukemias, parasites including those resistant to usual chemotherapeutic agents and as reversal agents | IVAX International GmbH (CH) | 2004-01-08 | — | — | US | claimed |
| WO-2003054106-A1 | GLYCERIN TRIESTER PLASTICIZER | FERRO CORPORATION (US) | 2003-07-03 | — | — | WO | claimed |
| US-20030116750-A1 | Glycerin triester plasticizer | POLYMER ADDITIVES, INC. | 2003-06-26 | — | — | US | claimed |
| US-6579869-B1 | Hydrolysis, esterification | ONCOPHARM CORPORATION | 2003-06-17 | — | — | US | claimed |
| EP-0672249-B1 | USE OF CAPILLARY ELECTROPHORESIS FOR QUANTITATING THE CONCENTRATION OF PROTEIN COMPONENTS AND OF THE TOTAL PROTEIN IN FLUIDS | BECKMAN COULTER INC (US) | 1999-05-12 | — | — | EP | claimed |
| US-5490909-A | Use of capillary electrophoresis for quantitating the concentration of protein components and of the total protein in fluids | BECKMAN INSTRUMENTS, INC. (US) | 1996-02-13 | — | — | US | claimed |
| EP-0672249-A1 | USE OF CAPILLARY ELECTROPHORESIS FOR QUANTITATING THE CONCENTRATION OF PROTEIN COMPONENTS AND OF THE TOTAL PROTEIN IN FLUIDS | BECKMAN INSTRUMENTS, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995010041-A1 | USE OF CAPILLARY ELECTROPHORESIS FOR QUANTITATING THE CONCENTRATION OF PROTEIN COMPONENTS AND OF THE TOTAL PROTEIN IN FLUIDS | BECKMAN INSTRUMENTS, INC. (US) | 1995-04-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006064-A1 | Cephalotaxanes, their method of preparation and their use in treatment of cancers, leukemias, parasites including those resistant to usual chemotherapeutic agents and as reversal agents | MCL1, CYCS, CYC1 | AKR1C4 2459/4885AKR1C3 1142/4885AKR1C2 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.