Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961149 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL36412 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL156030 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL5489911 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL8595697 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1244582 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1721398 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL111090 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1245246 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL643109 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044393-B1 | PROCESS FOR PREPARING A(N) (METH)ACRYLIC RESIN MODIFIED WITH EPSILON-CAPROLACTONE AND HAVING HYDROXYL GROUPS | Degussa Aktiengesellschaft (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0044393-A2 | Process for preparing a(n) (meth)acrylic resin modified with epsilon-caprolactone and having hydroxyl groups | Degussa Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |