Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123628 | 0.96 | PTGS1 (0.56) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11360177 | 0.94 | PTGS1 (0.53) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11358244 | 0.91 | PTGS1 (0.54) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11388339 | 0.90 | PTGS1 (0.59) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL10999919 | 0.88 | L3MBTL1 (0.52) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL10999916 | 0.88 | L3MBTL1 (0.52) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11378592 | 0.87 | PTGS1 (0.60) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11121444 | 0.86 | MAPT (0.54) | MAPTTDP1NR1I2SLC22A6SLC22A8 | |
| SCHEMBL11153948 | 0.85 | NR1I2 (0.41) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11355939 | 0.85 | PTGS1 (0.54) | PTGS1L3MBTL1MAPTTDP1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58039687-A | — | — | None | — | — | JP | disclosed |
| EP-0049309-B1 | CEPHEM DERIVATIVES, PROCESS FOR PRODUCING THEREOF, AND ANTIBACTERIAL AGENTS COMPRISING SAID COMPOUNDS | Eisai Co., Ltd. (JP) | 1984-05-09 | — | — | EP | disclosed |
| JP-S5839687-A | PREPARATION OF 3-(1-CARBOXYMETHYL-5-TETRAZOLYL) THIOMETHYL-3-CEPHEM DERIVATIVE | EISAI CO LTD | 1983-03-08 | — | — | JP | disclosed |