Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 2/20 | 0.74 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119566 | 0.90 | BIRC2 (0.60) | BIRC2MME | |
| SCHEMBL7320279 | 0.85 | BIRC2 (0.76) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL10956146 | 0.83 | BIRC2 (0.57) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL10952896 | 0.81 | BIRC2 (0.55) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL10956206 | 0.81 | BIRC2 (0.55) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL10948445 | 0.81 | BIRC2 (0.55) | BIRC2ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL7309896 | 0.81 | BIRC2 (0.70) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL9755830 | 0.81 | BIRC2 (0.70) | BIRC2MME | |
| SCHEMBL7320818 | 0.81 | BIRC2 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7321243 | 0.81 | BIRC2 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038046-B1 | PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-29 | — | — | EP | disclosed |