SCHEMBL10948445

SCHEMBL10948445

CCOC(=O)CCN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 1/20 0.55
ALDH1A1 P00352 1/20 0.52
THRB P10828 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CAPN1 P07384 1/20 0.50
POLB P06746 1/20 0.48
PSMB5 P28074 1/20 0.47
CTSD P07339 1/20 0.47
CA12 O43570 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10956146 0.89 BIRC2 (0.57) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL10952896 0.87 BIRC2 (0.55) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL10947650 0.84 BIRC2 (0.59) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL7374244 0.83 MME (0.57)
SCHEMBL10956206 0.83 BIRC2 (0.55) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL10952813 0.82 BIRC2 (0.54) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL11123333 0.81 BIRC2 (0.74) BIRC2ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL7589289 0.81 MMP1 (0.64)
SCHEMBL10662173 0.81 MME (0.58) CAPN1PSMB5
SCHEMBL23616326 0.81 ALDH1A1 (0.66) BIRC2ALDH1A1THRBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513009-A GLYCINE, ALANINE AND SERINE DERIVATIVES SOCIETE CIVILE BIOPROJET (FR) 1985-04-23 US disclosed