Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.69 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320279 | 0.92 | BIRC2 (0.76) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7314248 | 0.84 | BIRC2 (0.66) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7319199 | 0.82 | MME (0.71) | BIRC2MME | |
| SCHEMBL7319202 | 0.82 | MME (0.71) | BIRC2MME | |
| SCHEMBL7319195 | 0.82 | MME (0.71) | BIRC2MME | |
| SCHEMBL7321398 | 0.82 | MME (0.71) | BIRC2MME | |
| SCHEMBL7309896 | 0.82 | BIRC2 (0.70) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7321243 | 0.81 | BIRC2 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7313729 | 0.81 | BIRC2 (0.62) | BIRC2MMECYP2C9 | |
| SCHEMBL7321252 | 0.81 | BIRC2 (0.62) | BIRC2MMECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |