Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA6 | P17658 | 9/20 | 0.64 |
| ▸ | KCNA3 | P22001 | 9/20 | 0.64 |
| ▸ | KCNA4 | P22459 | 9/20 | 0.64 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.64 |
| ▸ | VIP | P01282 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Keramadine SCHEMBL11123417 | 1.00 | KCNA6 (0.64) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL21182348 | 0.78 | KCNA6 (1.00) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL13036733 | 0.78 | KCNA6 (1.00) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL13036735 | 0.74 | KCNA6 (0.67) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL15228546 | 0.70 | KCNA6 (0.57) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL15232609 | 0.70 | KCNA6 (0.57) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL31722801 | 0.68 | KCNA6 (0.64) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL15243719 | 0.67 | KCNA6 (0.51) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL23952430 | 0.64 | CREBBP (0.67) | KCNA6KCNA3KCNA4KCNA5VIP | |
| SCHEMBL15598660 | 0.64 | PKM (0.48) | KCNA6KCNA3KCNA4KCNA5VIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59231085-A | — | — | None | — | — | JP | disclosed |
| CN-117402090-A | Application of DES catalyst in ortho-position amino bromide and synthesis method of ortho-position amino bromide | 大连大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-112778155-B | Tucarbaryl derivatives and uses thereof | 大连万春布林医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| JP-S59231085-A | ALKALOID | MITSUBISHI CHEM IND LTD | 1984-12-25 | — | — | JP | disclosed |