Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DNM2 | P50570 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123565 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11127867 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11121805 | 0.98 | SMN1; SMN2 (0.41) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11124587 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11123146 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL8707780 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11123645 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1726232 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11124219 | 0.86 | ADRA2A (0.40) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11125149 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030350-B1 | METHOD FOR REDUCING THE TERMINAL CARBOXYL GROUP CONTENT OF A SATURATED POLYESTER, A SATURATED POLYESTER HAVING A REDUCED TERMINAL CARBOXYL GROUP CONTENT, AND A MOLDED ARTICLE COMPOSED OF SUCH A SATURATED POLYESTER | TEIJIN LIMITED (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4351936-A | COMPRISING ENDCAPPING WITH AN OXAZOLINE OR OXAZINE | TEIJIN LIMITED (JP) | 1982-09-28 | — | — | US | disclosed |
| EP-0030350-A1 | Method for reducing the terminal carboxyl group content of a saturated polyester, a saturated polyester having a reduced terminal carboxyl group content, and a molded article composed of such a saturated polyester | TEIJIN LIMITED (JP) | 1981-06-17 | — | — | EP | disclosed |