Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CDA | P32320 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305941 | 0.90 | KDM4E (0.52) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL4310230 | 0.90 | KDM4E (0.52) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL8368934 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL8047049 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL1001272 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL30195858 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL8371824 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL31265252 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL1319619 | 0.83 | ADORA3 (0.56) | KDM4EPKMALDH1A1TP53HTT | |
| SCHEMBL11284917 | 0.82 | ATIC (0.56) | SMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043722-B1 | BETA-D-ARABINOFURANOSYLIMIDAZO (4,5-C)PYRIDINE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4315000-A | β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-02-09 | — | — | US | disclosed |
| EP-0043722-A1 | Beta-D-Arabinofuranosylimidazo (4,5-c)pyridine compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1982-01-13 | — | — | EP | disclosed |