Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033856 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2169173 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL6497412 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16666241 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL720136 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30374910 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL26091921 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL22411301 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11396272 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21928125 | 0.72 | TTR (0.45) | ALDH1A1GAAHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034917-B1 | 2-SUBSTITUTED-5-TRIFLUOROMETHYLPYRIDINES AND A PROCESS FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |
| US-4367336-A | 2-Substituted-5-trifluoromethylpyridines and process for producing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-01-04 | — | — | US | disclosed |