Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12724970 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL17180597 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAHTTL3MBTL1KMT2A | |
| SCHEMBL6210015 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAHTTL3MBTL1KMT2A | |
| SCHEMBL2169173 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL6033856 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL24423759 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL29585372 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL11123776 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL6497412 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAAHTTL3MBTL1MEN1 | |
| SCHEMBL16666241 | 0.78 | ALDH1A1 (0.58) | ALDH1A1GAAHTTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735764-B | Method for recovering 2-cyano-3-chloro-5-trifluoromethylpyridine rectifying still residue | 内蒙古佳瑞米精细化工有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114478365-A | Purification method of 2-aminomethyl-3-chloro-5-trifluoromethylpyridine acetate | 大连九信作物科学有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112390748-B | Preparation method of 2-cyano-3-fluoro-5-trifluoromethylpyridine | 内蒙古佳瑞米精细化工有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-215946780-U | 2-cyano-3-chlorine-5-trifluoromethyl pyridine byproduct potassium fluoride recovery unit | 内蒙古佳瑞米精细化工有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113735764-A | Method for recovering 2-cyano-3-chloro-5-trifluoromethylpyridine rectifying still residue | 内蒙古佳瑞米精细化工有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-213493653-U | 2-cyano-3-chlorine-5-trifluoromethyl pyridine continuous reaction device | 内蒙古佳瑞米精细化工有限公司 | 2021-06-22 | — | — | CN | claimed |
| CN-112552231-A | Synthetic method of 2- (3-chloro-5- (trifluoromethyl) pyridine-2-yl) ethylamine | 南京正荣医药化学有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-112390748-A | Preparation method of 2-cyano-3-fluoro-5-trifluoromethylpyridine | 内蒙古佳瑞米精细化工有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-112390747-A | Combined preparation method of 2-cyano-3-chloro-5-trifluoromethylpyridine and succinonitrile | 内蒙古佳瑞米精细化工有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-112390746-A | Method for inhibiting generation of 2-cyano-3-chloro-5-trifluoromethylpyridine precursor impurity | 内蒙古佳瑞米精细化工有限公司 | 2021-02-23 | — | — | CN | claimed |
| US-7456290-B2 | Process for the preparation of 2-aminomethylpyridine derivative | BAYER CROPSCIENCE S.A. (FR) | 2008-11-25 | — | — | US | claimed |
| EP-1311483-B1 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYL-HALOGEN-PYRIDINES | BAYER CROPSCIENCE SA (FR) | 2006-12-20 | — | — | EP | claimed |
| US-6921828-B2 | Processes for the preparation of 2-aminomethlpyridines and the 2-cyanopyridines used in their preparation | BAYER CROPSCIENCE S.A. (FR) | 2005-07-26 | — | — | US | claimed |
| US-20040049048-A1 | Novel process | BAYER CROPSCIENCE LIMITED (GB) | 2004-03-11 | — | — | US | claimed |
| EP-1311483-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINES | Bayer CropScience S.A. (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1199305-A1 | Process for the preparation of 2-aminomethylpyridines | AVENTIS CROPSCIENCE S.A. (FR) | 2002-04-24 | — | — | EP | claimed |
| WO-2002016322-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOETHYLPYRIDINES | BAYER CROPSCIENCE SA (FR) | 2002-02-28 | — | — | WO | claimed |
| EP-0034917-B1 | 2-SUBSTITUTED-5-TRIFLUOROMETHYLPYRIDINES AND A PROCESS FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-08-08 | — | — | EP | claimed |
| US-4367336-A | 2-Substituted-5-trifluoromethylpyridines and process for producing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-01-04 | — | — | US | claimed |
| EP-0034917-A1 | 2-Substituted-5-trifluoromethylpyridines and a process for producing the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-09-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049048-A1 | Novel process | UGT1A4, SULT1A1, CYP4A11 | ALDH1A1 93/4885GAA 158/4885HTT 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.