Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.65 |
| ▸ | FCER2 | P06734 | 2/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.64 |
| ▸ | MME | P08473 | 2/20 | 0.62 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122512 | 1.00 | MMP1 (0.65) | MMP1FCER2LTA4HMMEBIRC2 | |
| SCHEMBL9556647 | 0.92 | FCER2 (0.67) | MMP1FCER2MMEBIRC2ERAP2 | |
| SCHEMBL11122734 | 0.90 | MME (0.76) | LTA4HMMEBIRC2MMP2MMP7 | |
| SCHEMBL11119164 | 0.90 | MME (0.76) | LTA4HMMEBIRC2MMP2MMP7 | |
| SCHEMBL11122736 | 0.90 | MME (0.76) | LTA4HMMEBIRC2MMP2MMP7 | |
| SCHEMBL11122302 | 0.90 | MME (0.76) | LTA4HMMEBIRC2MMP2MMP7 | |
| SCHEMBL11119167 | 0.90 | MME (0.76) | LTA4HMMEBIRC2MMP2MMP7 | |
| SCHEMBL11404199 | 0.87 | MME (0.81) | MMP1FCER2MME | |
| SCHEMBL11404202 | 0.87 | MME (0.81) | MMP1FCER2MME | |
| SCHEMBL11119566 | 0.86 | BIRC2 (0.60) | MMP1FCER2MMEBIRC2ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038046-B1 | PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-29 | — | — | EP | disclosed |
| EP-0038046-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-21 | — | — | EP | disclosed |