Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 2/20 | 0.67 |
| ▸ | MME | P08473 | 2/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.67 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.60 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404199 | 0.92 | MME (0.81) | FCER2MMEMMP1 | |
| SCHEMBL11122512 | 0.92 | MMP1 (0.65) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL11123808 | 0.92 | MMP1 (0.65) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL11404202 | 0.92 | MME (0.81) | FCER2MMEMMP1 | |
| SCHEMBL31516083 | 0.89 | ERAP2 (0.64) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL26660373 | 0.89 | FCER2 (0.60) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL11126476 | 0.88 | FCER2 (0.67) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL11126472 | 0.88 | FCER2 (0.67) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL2487473 | 0.87 | LTA4H (0.62) | FCER2MMEMMP1ERAP2ERAP1 | |
| SCHEMBL12038997 | 0.87 | LTA4H (0.62) | FCER2MMEMMP1ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |