Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SHBG | P04278 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125309 | 1.00 | CYP19A1 (0.57) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11201705 | 0.91 | CYP19A1 (0.58) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11600208 | 0.91 | CYP19A1 (0.58) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11600212 | 0.91 | CYP19A1 (0.58) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL6566539 | 0.88 | CYP19A1 (0.61) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL6566545 | 0.88 | CYP19A1 (0.61) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11294657 | 0.83 | CYP19A1 (0.51) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11294655 | 0.83 | CYP19A1 (0.51) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11305361 | 0.83 | CYP19A1 (0.51) | CYP19A1ARNR3C1LMNAMEN1 | |
| SCHEMBL11305366 | 0.83 | CYP19A1 (0.51) | CYP19A1ARNR3C1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039311-B1 | HALOGENATED STEROIDS | CIBA-GEIGY AG (CH) | 1984-07-11 | — | — | EP | claimed |