Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | AR | P10275 | 5/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SHBG | P04278 | 2/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201705 | 1.00 | CYP19A1 (0.58) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL11600208 | 1.00 | CYP19A1 (0.58) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL11125309 | 0.91 | CYP19A1 (0.57) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL11125312 | 0.91 | CYP19A1 (0.57) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL6566539 | 0.89 | CYP19A1 (0.61) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL6566545 | 0.89 | CYP19A1 (0.61) | CYP19A1ARHIF1ANR3C1LMNA | |
| SCHEMBL11311598 | 0.84 | PGR (0.68) | ARHIF1ANR3C1LMNAKMT2A | |
| SCHEMBL11311611 | 0.84 | PGR (0.68) | ARHIF1ANR3C1LMNAKMT2A | |
| SCHEMBL11313619 | 0.84 | PGR (0.68) | ARHIF1ANR3C1LMNAKMT2A | |
| SCHEMBL9862493 | 0.83 | HSD17B10 (0.71) | ARHIF1ANR3C1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088537-A | BIOTRANSFORMATION | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |