Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.65 |
| ▸ | AR | P10275 | 4/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125393 | 1.00 | PGR (0.65) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11125425 | 1.00 | PGR (0.65) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11236322 | 0.93 | PGR (0.72) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11126579 | 0.93 | PGR (0.72) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11236326 | 0.93 | PGR (0.72) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL10427850 | 0.92 | PGR (0.58) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL10427908 | 0.92 | PGR (0.58) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11124736 | 0.91 | ABCB11 (0.67) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11127564 | 0.91 | ABCB11 (0.67) | PGRARADRA1AADORA3CHRM1 | |
| SCHEMBL11236533 | 0.91 | PGR (0.64) | PGRARADRA1AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039311-B1 | HALOGENATED STEROIDS | CIBA-GEIGY AG (CH) | 1984-07-11 | — | — | EP | claimed |
| US-4361558-A | PREPARATION OF THESE ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-11-30 | — | — | US | claimed |
| US-4361558-A | PREPARATION OF THESE ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |