Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705448 | 0.80 | ALOX5 (0.59) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL5010140 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL15064560 | 0.77 | CNR2 (1.00) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL15064748 | 0.75 | CNR2 (1.00) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL8807915 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10954413 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10316495 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL14557293 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL4116469 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL131813 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRCNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057661-B1 | PROCESS FOR THE PRODUCTION OF LEUCO TRIARYL METHANE COMPOUNDS | CIBA-GEIGY AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| EP-0057661-A2 | Process for the production of leuco triaryl methane compounds | CIBA-GEIGY AG (CH) | 1982-08-11 | — | — | EP | disclosed |