Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127808 | 0.84 | CA9 (0.41) | CA12CA9MAPTKMT2AMEN1 | |
| SCHEMBL11126116 | 0.78 | LIMK1 (0.49) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11127473 | 0.76 | CA12 (0.46) | CA12CA9MAPTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11128193 | 0.76 | LIMK1 (0.47) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11129704 | 0.72 | SMN1; SMN2 (0.40) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11129548 | 0.71 | CA9 (0.41) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11125007 | 0.68 | SMN1; SMN2 (0.40) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11128299 | 0.66 | SMN1; SMN2 (0.41) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11127857 | 0.66 | NPY5R (0.40) | CA12CA9MAPTKMT2ALMNA | |
| SCHEMBL11128296 | 0.66 | SMN1; SMN2 (0.41) | CA12CA9MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | claimed |
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | disclosed |