Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128296 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9APTGS2CYP1A2 | |
| SCHEMBL11126116 | 0.68 | LIMK1 (0.49) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11127473 | 0.67 | CA12 (0.46) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11128193 | 0.67 | LIMK1 (0.47) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11127262 | 0.66 | CA12 (0.45) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11129548 | 0.65 | CA9 (0.41) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11127808 | 0.64 | CA9 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1CA12 | |
| SCHEMBL11129704 | 0.63 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ACYP1A2LMNA | |
| SCHEMBL11125007 | 0.62 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ACYP1A2LMNA | |
| SCHEMBL11128709 | 0.60 | HSD17B10 (0.43) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | disclosed |