Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11128193 | 0.98 | LIMK1 (0.47) | LIMK1CA12CA9ALDH1A1KDM4E | |
| SCHEMBL11128266 | 0.80 | HRH4 (0.39) | ALDH1A1KDM4EMEN1KMT2AHRH4 | |
| SCHEMBL11127473 | 0.79 | CA12 (0.46) | LIMK1CA12CA9ALDH1A1KDM4E | |
| SCHEMBL11129709 | 0.78 | CSNK2B (0.45) | CA9HRH4MAPTNPC1RAB9A | |
| SCHEMBL11125003 | 0.78 | AHR (0.42) | CA12CA9ALDH1A1KMT2AHRH4 | |
| SCHEMBL11126598 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2AHRH4LMNA | |
| SCHEMBL11127262 | 0.78 | CA12 (0.45) | LIMK1CA12CA9ALDH1A1KDM4E | |
| SCHEMBL11128820 | 0.78 | MCL1 (0.36) | ALDH1A1KDM4EMEN1KMT2AHRH4 | |
| SCHEMBL11125004 | 0.76 | ATP1A1 (0.39) | KDM4EMAPTTSHRLMNA | |
| SCHEMBL11129704 | 0.74 | SMN1; SMN2 (0.40) | LIMK1CA12CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | claimed |
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | disclosed |