Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | PGR | P06401 | 9/20 | 0.58 |
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126591 | 1.00 | ABCB11 (0.72) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11274986 | 0.92 | ABCB11 (0.79) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL22171557 | 0.92 | ABCB11 (0.79) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11413999 | 0.92 | ABCB11 (0.79) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11124571 | 0.92 | ABCB11 (0.79) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11123589 | 0.92 | ABCB11 (0.79) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11122098 | 0.91 | PGR (0.69) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11126100 | 0.91 | PGR (0.69) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL11122100 | 0.91 | PGR (0.69) | ABCB11PGRARCYP3A4HIF1A | |
| SCHEMBL8909765 | 0.89 | PGR (0.66) | ABCB11PGRARCYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029924-B1 | 6-ALPHA-FLUORO-16-METHYL-PREDNISOLONE-17,21 DIESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | STEROSYNT Ltd. (GB) | 1984-08-15 | — | — | EP | claimed |