Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126598 | 0.84 | ALDH1A1 (0.51) | HRH4PIM1PIM3PIM2KMT2A | |
| SCHEMBL11129709 | 0.84 | CSNK2B (0.45) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL11126116 | 0.80 | LIMK1 (0.49) | HRH4MAPTKDM4EMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL11128193 | 0.78 | LIMK1 (0.47) | HRH4MAPTKDM4EMEN1MAPK1 | |
| SCHEMBL11128820 | 0.71 | MCL1 (0.36) | HRH4MAPTKDM4EMEN1KMT2A | |
| SCHEMBL17037127 | 0.70 | MAPT (0.53) | ALPGCSNK2A2CSNK2BMAPTKDM4E | |
| SCHEMBL15428294 | 0.69 | PIM1 (0.47) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL13563987 | 0.67 | MAPT (0.46) | ALPGCSNK2A2CSNK2BMAPTKDM4E | |
| SCHEMBL27058861 | 0.67 | HRH4 (0.50) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL4594004 | 0.67 | ALDH1A1 (0.71) | HRH4PIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | claimed |
| US-4420476-A | Benzofuro[3,2-c]pyrazol-3-amine derivatives | Averst McKenna & Harrison, Inc. (CA) | 1983-12-13 | — | — | US | disclosed |