Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125764 | 0.84 | FFAR1 (0.42) | IDO1MAPTHRH4HRH3 | |
| SCHEMBL11125161 | 0.79 | TSHR (0.46) | MAPTPOLBHRH3 | |
| SCHEMBL29262951 | 0.77 | CYP3A4 (0.46) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL8069435 | 0.77 | HRH3 (0.36) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL13370306 | 0.77 | GFER (0.48) | CYP3A4MAPT | |
| SCHEMBL1978687 | 0.77 | TAAR1 (0.42) | IDO1MEN1POLBKMT2A | |
| SCHEMBL5347405 | 0.77 | ESR1 (0.48) | IDO1MAPTKMT2A | |
| SCHEMBL574859 | 0.77 | TAAR1 (0.42) | IDO1 | |
| SCHEMBL10056649 | 0.77 | PPARA (0.35) | MEN1POLBKMT2A | |
| SCHEMBL18931456 | 0.76 | CYP3A4 (0.34) | CYP3A4IDO1APPHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431564-A | 4'-/2-ALKYLOXYETHYL/-4-CYANOBI-OR TERPHENYLS; DISPLAYING; IODINATION AND CYANATION THE ESTER DERIVATIVE | CHISSO CORPORATION (JP) | 1984-02-14 | — | — | US | claimed |
| JP-58041854-A | — | — | None | — | — | JP | disclosed |
| JP-S5841854-A | 4'-(BETA-ALKYLOXYETHYL)-4-CYANOBIPHENYL | CHISSO CORP | 1983-03-11 | — | — | JP | disclosed |