Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307672 | 0.82 | IDO1 (0.46) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL8389404 | 0.81 | ESR1 (0.65) | ESR1ESR2CA2CA12CA1 | |
| Hydroquinone SCHEMBL438337 | 0.81 | HSD17B10 (0.42) | ESR1ESR2CA2CA12CA1 | |
| SCHEMBL13370306 | 0.81 | GFER (0.48) | ALDH1A1TDP1NPC1MAPTRAB9A | |
| SCHEMBL1978687 | 0.81 | TAAR1 (0.42) | ALDH1A1TAAR1KMT2AIDO1 | |
| SCHEMBL10056649 | 0.81 | PPARA (0.35) | KMT2A | |
| SCHEMBL574859 | 0.81 | TAAR1 (0.42) | TAAR1IDO1SMN1; SMN2 | |
| SCHEMBL144596 | 0.80 | MAPT (0.42) | CA2CA1CA9ALDH1A1TAAR1 | |
| SCHEMBL11125764 | 0.78 | FFAR1 (0.42) | TAAR1IDO1MAPT | |
| SCHEMBL10527969 | 0.77 | ESR1 (0.59) | ESR1ESR2CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | claimed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | claimed |
| US-6989465-B1 | S-(−)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of S-(−)betaxolo | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-01-24 | — | — | US | claimed |
| JP-10168036-A | — | — | None | — | — | JP | disclosed |
| CN-101665441-B | Method for preparing l-betaxolol hydrochloride | ANHUI QINGYUN PHARMACEUTICAL AND CHEMICAL CO LTD | 2013-04-10 | — | — | CN | disclosed |
| CN-101665441-A | Method for preparing l-betaxolol hydrochloride | ANHUI QINGYUN PHARMACEUTICAL A | 2010-03-10 | — | — | CN | disclosed |
| CN-100532355-C | Technique for synthesizing levorotatory betaxolol hydrochloride | UNIV ZHENGZHOU (CN) | 2009-08-26 | — | — | CN | disclosed |
| CN-100528832-C | Technique of synthesizing levorotatory betaxolol hydrochloride | HONGMIN LIU (CN) | 2009-08-19 | — | — | CN | disclosed |
| CN-101085742-A | Technique for synthesizing levorotatory betaxolol hydrochloride | UNIV ZHENGZHOU (CN) | 2007-12-12 | — | — | CN | disclosed |
| CN-101012175-A | Technique of synthesizing levorotatory betaxolol hydrochloride | LIU HONGMIN (CN) | 2007-08-08 | — | — | CN | disclosed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | disclosed |
| US-6989465-B1 | S-(−)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of S-(−)betaxolo | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-01-24 | — | — | US | disclosed |
| JP-H10168036-A | LIQUID CRYSTAL COMPOUND | ASAHI DENKA KOGYO KK | 1998-06-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | ADRB1, ADRB2, ADRA1A | ESR1 3216/4885ESR2 447/4885CA2 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.