SCHEMBL11129656

SCHEMBL11129656

C=CCOC(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SCN1A P35498 3/20 0.46
SCN2A Q99250 3/20 0.46
SCN3A Q9NY46 3/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
ADRA2A P08913 1/20 0.46
CHRM1 P11229 1/20 0.46
TSHR P16473 1/20 0.46
ADRA2B P18089 1/20 0.46
CHRM3 P20309 1/20 0.46
SLC6A2 P23975 1/20 0.46
HRH2 P25021 1/20 0.46
HTR2A P28223 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28026900 0.89 IDO1 (0.53) LMNACYP2D6CYP1A2CHRM2ADRA2A
SCHEMBL3093470 0.83 MEN1 (0.46) MEN1KMT2ATSHRHTR2AKDM4E
SCHEMBL4830716 0.82 MEN1 (0.38) MEN1KMT2ASCN1ASCN2ASCN3A
SCHEMBL27490058 0.81 MEN1 (0.45) MEN1KMT2ACYP2D6TSHRHTR2A
SCHEMBL873640 0.79 MEN1 (0.47) MEN1KMT2ASCN1ASCN2ASCN3A
SCHEMBL5599318 0.79 MEN1 (0.44) MEN1KMT2ALMNACYP2D6CYP1A2
SCHEMBL9279164 0.79 MEN1 (0.44) MEN1KMT2ASCN1ASCN2ASCN3A
SCHEMBL7334316 0.79 MEN1 (0.44) MEN1KMT2ALMNAHTR2AKDM4E
SCHEMBL1906076 0.79 MEN1 (0.44) MEN1KMT2ACYP2D6HTR2AHRH1
SCHEMBL7110913 0.79 MEN1 (0.44) MEN1KMT2AHTR2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844426-A Bis anisole derivative synthesis method UNIV CHONGQING 2015-08-19 CN claimed
JP-59221358-A None JP disclosed
CN-104844426-A Bis anisole derivative synthesis method UNIV CHONGQING 2015-08-19 CN disclosed
CN-104447154-A Method for removing hydroxy (mercapto), alkoxy, acetyl and allyloxy groups UNIV CHONGQING 2015-03-25 CN disclosed
EP-1930308-A1 Pharmaceutical agents for the treatment of cerebral amyloidosis NYMOX CORPORATION (CA) 2008-06-11 EP disclosed
JP-S59221358-A BENZHYDROL ALKYL ETHER COMPOUND HODOGAYA CHEM CO LTD 1984-12-12 JP disclosed