SCHEMBL873640

SCHEMBL873640

C=CCOC(C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HCAR2 Q8TDS4 1/20 0.40
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TAAR1 Q96RJ0 3/20 0.38
TACR1 P25103 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC22A1 O15245 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36
CYP2D6 P10635 1/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27400827 0.85 NR3C1 (0.41) MEN1KMT2AALDH1A1NR3C1PGR
SCHEMBL11272926 0.84 IDO1 (0.38) MEN1KMT2ANR3C1PGRSMN1; SMN2
SCHEMBL21517771 0.82 HCAR2 (0.41) HCAR2TAAR1TACR1SMN1; SMN2LMNA
SCHEMBL8645353 0.81 ESR1 (0.43) MEN1KMT2ACYP2C19ALDH1A1TAAR1
SCHEMBL503318 0.81 NR3C1 (0.38) MEN1KMT2ANR3C1PGRSLC6A4
SCHEMBL13370305 0.81 MEN1 (0.35) MEN1KMT2AALDH1A1NR3C1PGR
SCHEMBL2322250 0.80 HCAR2 (0.43) MEN1KMT2AHCAR2TAAR1TACR1
SCHEMBL11259115 0.79 ALDH1A1 (0.47) CYP2C19ALDH1A1CYP3A4SMN1; SMN2CYP1A2
SCHEMBL11129656 0.79 MEN1 (0.46) MEN1KMT2ACYP2C19SMN1; SMN2LMNA
SCHEMBL3093470 0.79 MEN1 (0.46) MEN1KMT2ACYP2C19ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20230004023-A1 DIFFRACTIVE CONTACT LENSES ALCON INC. (CH) 2023-01-05 US claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
US-6878781-B2 Poly(arylene ether)-containing thermoset composition in powder form, method for the preparation thereof, and articles derived therefrom GENERAL ELECTRIC (US) 2005-04-12 US claimed
JP-2004526030-A 2004-08-26 JP claimed
US-6770107-B2 CURABLE THERMOPLASTIC ELASTOMERS COMPRISING POLYPHENYL ETHERS, DIAMOND, CARBIDE OR NITRIDE PARTICLES, ACRYLIC AND ALLYL HOMOPOLYMERS, MOLDED TO FORM CUTTING OR GRINDING TOOLS HAVING WEAR RESISTANCE GENERAL ELECTRIC COMPANY 2004-08-03 US claimed
EP-1373409-A1 ABRASIVE-FILLED THERMOSET COMPOSITION AND ITS PREPARATION, AND ABRASIVE-FILLED ARTICLES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-01-02 EP claimed
EP-1373410-A1 POLY(ARYLENE ETHER)-CONTAINING THERMOSET COMPOSITION IN POWDER FORM, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2004-01-02 EP claimed
US-20030153641-A1 Curable thermoplastic elastomers comprising polyphenyl ethers, diamond, carbide or nitride particles, acrylic and allyl homopolymers, molded to form cutting or grinding tools having wear resistance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2003-08-14 US claimed
US-6593391-B2 Polyphenylene ether blend GENERAL ELECTRIC COMPANY 2003-07-15 US claimed
US-20030018116-A1 Abrasive-filled thermoset composition and its preparation, and abrasive-filled articles and their preparation DIAMOND INNOVATIONS, INC. 2003-01-23 US claimed
US-20020173597-A1 Poly(arylene ether)-containing thermoset composition in powder form, method for the preparation thereof, and articles derived therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-11-21 US claimed
WO-2002077102-A1 ABRASIVE-FILLED THERMOSET COMPOSITION AND ITS PREPARATION, AND ABRASIVE-FILLED ARTICLES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2002-10-03 WO claimed
WO-2002077103-A1 POLY(ARYLENE ETHER)-CONTAINING THERMOSET COMPOSITION IN POWDER FORM, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-10-03 WO claimed
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 WO disclosed
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-14 US disclosed
US-4521635-A USING ACID-TREATED ALUMINA CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US disclosed
US-4521636-A CONDENSATION OF ALPHA ALKYLBENZYL ALCOHOL IN PRESENCE OF ALUMINUM SULFATE CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE MYO1G, STRA6, GJA1 MEN1 191/4885KMT2A 1852/4885HCAR2 3749/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA MEN1 3136/4885KMT2A 4509/4885HCAR2 3782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.