Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MECP2 | P51608 | 1/20 | 0.49 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683724 | 0.79 | MAPT (0.46) | MAPTLMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL8796437 | 0.74 | KDM1A (0.43) | MAPTSMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL27290318 | 0.72 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1TDP1ERN1 | |
| SCHEMBL29575655 | 0.71 | MAPT (0.48) | MECP2MBD2MAPTNPSR1MEN1 | |
| SCHEMBL8951248 | 0.70 | MAPT (0.44) | MAPTNPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23216669 | 0.70 | KDM4E (0.48) | MECP2MBD2MAPTNPSR1MEN1 | |
| SCHEMBL29768426 | 0.70 | KDM4E (0.48) | MECP2MBD2MAPTNPSR1MEN1 | |
| SCHEMBL27294881 | 0.69 | MAPT (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL15858577 | 0.69 | KDM4E (0.57) | MECP2MBD2MAPTNPSR1MEN1 | |
| SCHEMBL4120535 | 0.68 | PRCP (0.50) | MAPTNPSR1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58032871-A | — | — | None | — | — | JP | disclosed |
| JP-S5832871-A | ARYLTHIAZOLIDINE COMPOUND | SANTEN PHARMACEUT CO LTD | 1983-02-25 | — | — | JP | disclosed |