Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683724 | 0.88 | MAPT (0.46) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL27296873 | 0.81 | MAPT (0.47) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL27294881 | 0.74 | MAPT (0.35) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL30683723 | 0.73 | ERN1 (0.48) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL8951248 | 0.73 | MAPT (0.44) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL11129658 | 0.72 | MECP2 (0.49) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL12767256 | 0.72 | MAPT (0.42) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL10791762 | 0.70 | MAPT (0.46) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL2359691 | 0.67 | CHRNB2 (0.39) | TDP1ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL30683721 | 0.67 | MAPT (0.50) | MAPTTDP1SMN1; SMN2ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039492-C | Herbicides | ZENECA LTD (GB) | 1998-08-12 | — | — | CN | disclosed |
| CN-1095066-A | Weedicide | ZENECA LTD (GB) | 1994-11-16 | — | — | CN | disclosed |