Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828622 | 0.81 | ALDH1A1 (0.43) | MAPTTDP1SMN1; SMN2IDO1CYP2D6 | |
| SCHEMBL10800761 | 0.76 | MTNR1A (0.50) | KDM1AMAPTTDP1MTNR1AIDO1 | |
| SCHEMBL7744554 | 0.75 | MAPT (0.53) | KDM1AMAPTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3396242 | 0.75 | MAPT (0.53) | KDM1AMAPTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27288856 | 0.75 | SMN1; SMN2 (0.51) | MAPTTDP1SMN1; SMN2ALDH1A1SLC6A3 | |
| SCHEMBL8951248 | 0.75 | MAPT (0.44) | MAPTTDP1SMN1; SMN2CYP2D6ALDH1A1 | |
| SCHEMBL11129658 | 0.74 | MECP2 (0.49) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL13811323 | 0.74 | KDM1A (0.52) | KDM1AMAPTTDP1MTNR1AIDO1 | |
| SCHEMBL27999354 | 0.74 | KDM1A (0.52) | KDM1AMAPTTDP1MTNR1AIDO1 | |
| SCHEMBL10640806 | 0.72 | KDM1A (0.50) | KDM1AMAPTTDP1MTNR1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772607-A1 | WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-14 | — | — | EP | claimed |
| US-5599825-A | ANTITUMOR AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1997-02-04 | — | — | US | claimed |
| WO-1996003393-A1 | WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-08 | — | — | WO | claimed |
| EP-0530827-A2 | Image forming process | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |