Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509142 | 0.85 | PDPK1 (0.46) | SIGMAR1PDPK1PLAU | |
| SCHEMBL44650 | 0.76 | SIGMAR1 (0.44) | SIGMAR1GRIN2BPLAUCYP11B2KDM1A | |
| SCHEMBL6721448 | 0.75 | SIGMAR1 (0.43) | SIGMAR1PDPK1PLAUIDO1 | |
| SCHEMBL6676676 | 0.73 | PLAU (0.45) | SIGMAR1PDPK1PLAUIDO1 | |
| SCHEMBL15547683 | 0.73 | SIGMAR1 (0.42) | SIGMAR1GRIN2BPDPK1PLAUCYP11B2 | |
| SCHEMBL10780065 | 0.73 | SIGMAR1 (0.42) | SIGMAR1PDPK1PLAUIDO1 | |
| SCHEMBL5255259 | 0.73 | PLAU (0.45) | SIGMAR1PDPK1PLAUIDO1 | |
| SCHEMBL30724832 | 0.73 | SIGMAR1 (0.42) | SIGMAR1PDPK1PLAUIDO1 | |
| SCHEMBL28525701 | 0.72 | SIGMAR1 (0.41) | SIGMAR1GRIN2BPDPK1PLAUCYP11B2 | |
| SCHEMBL30160953 | 0.72 | SIGMAR1 (0.41) | SIGMAR1GRIN2BPDPK1PLAUIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58177987-A | — | — | None | — | — | JP | disclosed |
| JP-S58177987-A | IMPROVEMENT IN THIOCHROMAN PRODUCTION | HOKKO CHEM IND CO LTD | 1983-10-18 | — | — | JP | disclosed |