Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255259 | 1.00 | PLAU (0.45) | PLAUSIGMAR1ANPEPIDO1HTR2A | |
| SCHEMBL14388742 | 0.78 | PLAU (0.39) | PLAUSIGMAR1ANPEPIDO1HTR2A | |
| SCHEMBL6721448 | 0.77 | SIGMAR1 (0.43) | PLAUSIGMAR1ANPEPIDO1PDPK1 | |
| SCHEMBL10780065 | 0.75 | SIGMAR1 (0.42) | PLAUSIGMAR1IDO1PDPK1 | |
| SCHEMBL30724832 | 0.75 | SIGMAR1 (0.42) | PLAUSIGMAR1IDO1PDPK1 | |
| SCHEMBL15547683 | 0.75 | SIGMAR1 (0.42) | PLAUSIGMAR1ANPEPIDO1PDPK1 | |
| SCHEMBL9722865 | 0.75 | SIGMAR1 (0.42) | PLAUSIGMAR1ANPEPIDO1HTR2A | |
| SCHEMBL28525701 | 0.73 | SIGMAR1 (0.41) | PLAUSIGMAR1ANPEPIDO1PDPK1 | |
| SCHEMBL30160953 | 0.73 | SIGMAR1 (0.41) | PLAUSIGMAR1ANPEPIDO1PDPK1 | |
| SCHEMBL11129686 | 0.73 | SIGMAR1 (0.44) | PLAUSIGMAR1IDO1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434580-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003030886-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC (US) | 2003-04-17 | — | — | WO | disclosed |