Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.45 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122771 | 1.00 | ADRB2 (0.45) | ADRB2ADRB1DPP4ADRB3ADRA1D | |
| Hydrochloric Acid SCHEMBL8855378 | 0.99 | ADRB2 (0.44) | ADRB2ADRB1DPP4ADRB3ADRA1D | |
| SCHEMBL11136288 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1CASR | |
| SCHEMBL11136281 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1CASR | |
| Oxalic Acid SCHEMBL11451371 | 0.84 | ADRB2 (0.43) | ADRB2ADRB1CASR | |
| SCHEMBL10770012 | 0.84 | ADRB3 (0.48) | ADRB2ADRB1DPP4ADRB3ADRA1D | |
| Hydrochloric Acid SCHEMBL11134351 | 0.84 | ADRB2 (0.54) | ADRB2ADRB1CASR | |
| SCHEMBL3366477 | 0.84 | ADRB3 (0.48) | ADRB2ADRB1DPP4ADRB3ADRA1D | |
| Hydrochloric Acid SCHEMBL10766903 | 0.83 | ADRB3 (0.49) | ADRB2ADRB1DPP4ADRB3ADRA1D | |
| Hydrochloric Acid SCHEMBL10766900 | 0.83 | ADRB3 (0.49) | ADRB2ADRB1DPP4ADRB3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047536-B1 | SUBSTITUTED PROPYLAMINES | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | disclosed |
| EP-0007206-B1 | PHENETHANOLAMINES, THEIR FORMULATIONS, PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| EP-0047536-A2 | Substituted propylamines | ELI LILLY AND COMPANY (US) | 1982-03-17 | — | — | EP | disclosed |
| EP-0007206-A1 | Phenethanolamines, their formulations, preparation and use | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |